Methamphetamine toxicity-induced calcineurin activation, nuclear translocation of nuclear factor of activated T-cells and elevation of cyclooxygenase 2 levels are averted by calpastatin overexpression in neuroblastoma SH-SY5Y cells

• Main Authors: Jirapa Chetsawang, Sutisa Nudmamud-Thanoi, Ruchee Phonchai, Zuroida Abubakar, Piyarat Govitrapong, Banthit Chetsawang
• Other Authors: Naresuan University
• Format: Article
• Published: 2019
• Subjects: Neuroscience; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/47261
• Institution: Mahidol University

© 2018 Elsevier B.V. Methamphetamine (METH) is an addictive stimulant drug that has many negative consequences, including toxic effects to the brain. Recently, the induction of inflammatory processes has been identified as a potential contributing factor to induce neuronal cell degeneration. It has...