Epigallocatechin-3-gallate prevents TGF-β1-induced epithelial-mesenchymal transition and fibrotic changes of renal cells via GSK-3β/β-catenin/Snail1 and Nrf2 pathways

Epigallocatechin-3-gallate prevents TGF-β1-induced epithelial-mesenchymal transition and fibrotic changes of renal cells via GSK-3β/β-catenin/Snail1 and Nrf2 pathways

© 2019 Several lines of evidence have demonstrated anti-fibrotic property of epigallocatechin-3-gallate (EGCG) in many tissues/organs but with unclear mechanisms. This study thus aimed to define cellular mechanisms underlying such protective effect of EGCG. HK-2 renal cells were treated with 5 ng/ml...

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Bibliographic Details
Main Authors: Rattiyaporn Kanlaya, Paleerath Peerapen, Angkhana Nilnumkhum, Sirikanya Plumworasawat, Kanyarat Sueksakit, Visith Thongboonkerd
Other Authors: Faculty of Medicine, Siriraj Hospital, Mahidol University
Format: Article
Published: 2020
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Nursing
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/49536
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/49536

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