Epigallocatechin-3-gallate prevents TGF-β1-induced epithelial-mesenchymal transition and fibrotic changes of renal cells via GSK-3β/β-catenin/Snail1 and Nrf2 pathways
© 2019 Several lines of evidence have demonstrated anti-fibrotic property of epigallocatechin-3-gallate (EGCG) in many tissues/organs but with unclear mechanisms. This study thus aimed to define cellular mechanisms underlying such protective effect of EGCG. HK-2 renal cells were treated with 5 ng/ml...
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Main Authors: | Rattiyaporn Kanlaya, Paleerath Peerapen, Angkhana Nilnumkhum, Sirikanya Plumworasawat, Kanyarat Sueksakit, Visith Thongboonkerd |
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Other Authors: | Faculty of Medicine, Siriraj Hospital, Mahidol University |
Format: | Article |
Published: |
2020
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/49536 |
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Institution: | Mahidol University |
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