Association of carbamazepine-induced Stevens–Johnson syndrome/toxic epidermal necrolysis with the HLA-B75 serotype or HLA-B*15:21 allele in Filipino patients

• Main Authors: Francis Capule, Pramote Tragulpiankit, Surakameth Mahasirimongkol, Jiraphun Jittikoon, Nuanjun Wichukchinda, Lara Theresa Alentajan-Aleta, Jay V. James Barit, Josephine Casanova-Gutierrez, Leonor Cabral-Lim, Jose Paciano Baltazar Reyes, Francisca Roa, Raymark Salonga, Katrina Faith San Gabriel, Catherine Lynn Silao
• Other Authors: University of the Philippines Manila
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/49559
• Institution: Mahidol University

© 2020, The Author(s), under exclusive licence to Springer Nature Limited. A case-control study was conducted to investigate the association of HLA-A alleles, HLA-B alleles including HLA-B*15:02 and HLA-B75 serotype with carbamazepine-induced SJS/TEN in Filipino patients. A retrospective review of m...