Differential contribution of pyruvate carboxylation to anaplerosis and cataplerosis during non-gluconeogenic and gluconeogenic conditions in HepG2 cells

• المؤلفون الرئيسيون: Siriluck Wattanavanitchakorn, Israr H. Ansari, Mahmoud El Azzouny, Melissa J. Longacre, Scott W. Stoker, Michael J. MacDonald, Sarawut Jitrapakdee
• مؤلفون آخرون: University of Wisconsin School of Medicine and Public Health
• التنسيق: مقال
• منشور في: 2020
• الموضوعات: Biochemistry, Genetics and Molecular Biology
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/50033

© 2019 Elsevier Inc. Pyruvate carboxylase (PC) is an anaplerotic enzyme that supplies oxaloacetate to mitochondria enabling the maintenance of other metabolic intermediates consumed by cataplerosis. Using liquid chromatography mass spectrometry (LC-MS) to measure metabolic intermediates derived from...