Pathogenic PSEN1 Glu184Gly mutation in a family from Thailand with probable autosomal dominant early onset Alzheimer’s disease

• Main Authors: Vorapun Senanarong, Seong Soo A. An, Vo van Giau, Chanin Limwongse, Eva Bagyinszky, Sang Yun Kim
• Other Authors: Seoul National University Bundang Hospital
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/53589
• Institution: Mahidol University

© 2020 by the authors. A pathogenic mutation in PSEN1 p.Glu184Gly was discovered in a Thai family with early onset Alzheimer’s disease (EOAD) as the first case in Asia. Proband patient presented memory impairment and anxiety at the age of 41 years. Family history was positive, since several family m...