Statistical considerations in the design and analysis of non-inferiority trials with binary endpoints in the presence of non-adherence: A simulation study
© 2020 Mo Y et al. Protocol non-adherence is common and poses unique challenges in the interpretation of trial outcomes, especially in non-inferiority trials. We performed simulations of a non-inferiority trial with a time-fixed treatment and a binary endpoint in order to: i) explore the impact of v...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/57766 |
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| Institution: | Mahidol University |