Statistical considerations in the design and analysis of non-inferiority trials with binary endpoints in the presence of non-adherence: A simulation study

© 2020 Mo Y et al. Protocol non-adherence is common and poses unique challenges in the interpretation of trial outcomes, especially in non-inferiority trials. We performed simulations of a non-inferiority trial with a time-fixed treatment and a binary endpoint in order to: i) explore the impact of v...

Full description

Saved in:
Bibliographic Details
Main Authors: Yin Mo, Cherry Lim, Mavuto Mukaka, Ben S. Cooper
Other Authors: National University Hospital, Singapore
Format: Article
Published: 2020
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/57766
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University