Perinatal Antiretroviral Intensification to Prevent Intrapartum HIV Transmission When Antenatal Antiretroviral Therapy Is Initiated Less Than 8 Weeks Before Delivery

• Main Authors: Marc Lallemant, Billy Amzal, Patumrat Sripan, Saïk Urien, Tim R. Cressey, Nicole Ngo-Giang-Huong, Virat Klinbuayaem, Boonsong Rawangban, Prapan Sabsanong, Thitiporn Siriwachirachai, Tapnarong Jarupanich, Prateep Kanjanavikai, Phaiboon Wanasiri, Suporn Koetsawang, Gonzague Jourdain, Sophie Le Coeur
• Other Authors: Université de Paris
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/58109
• Institution: Mahidol University

INTRODUCTION: Infants born to women living with HIV initiating combination antiretroviral therapy (cART) late in pregnancy are at high risk of intrapartum infection. Mother/infant perinatal antiretroviral intensification may substantially reduce this risk. METHODS: In this single-arm Bayesian trial,...