Inhibition of human immunodeficiency virus type 1 by niclosamide through mTORC1 inhibition

© 2020 The Author(s) Niclosamide has been known to inhibit a number of pH-dependent viruses via the neutralization of endosomal acidic pH. It has also been shown to disrupt the mTORC1 signaling pathway. The replication of many viruses requires mTORC1 activation. Here, we investigated the inhibitory...

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Bibliographic Details
Main Authors: Nattamon Niyomdecha, Ornpreya Suptawiwat, Chompunuch Boonarkart, Kunlakunya Jitobaom, Prasert Auewarakul
Other Authors: Thammasat University
Format: Article
Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/58426
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Institution: Mahidol University