Synthesis and neuroprotective effects of novel chalcone-triazole hybrids

• Main Authors: Pichjira Sooknual, Ratchanok Pingaew, Kamonrat Phopin, Waralee Ruankham, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul
• Other Authors: South Carolina Commission on Higher Education
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/59848
• Institution: Mahidol University

© 2020 Elsevier Inc. The development of novel neuroprotective agents is urgently needed for the treatment of neurodegenerative diseases, affecting aging individuals worldwide. In this study, a new set of chalcone-triazole hybrids (6a-g) was synthesized and evaluated for their biological properties i...