Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians

• Main Authors: Chuang Wei Wang, Wichittra Tassaneeyakul, Chun Bing Chen, Wei Ti Chen, Yu Chuan Teng, Cheng Yang Huang, Chonlaphat Sukasem, Chun Wei Lu, Yun Shien Lee, Siew Eng Choon, Nontaya Nakkam, Rosaline Chung Yee Hui, Yen Hua Huang, Ya Ching Chang, Yang Yu Wei Lin, Chee Jen Chang, Tsu Man Chiu, Wasun Chantratita, Parinya Konyoung, Chaw Ning Lee, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Warayuwadee Amornpinyo, Niwat Saksit, Pawinee Rerknimitr, Yu Huei Huang, Shang Hung Lin, Chao Kai Hsu, Cheng Chi Chan, Yu Lin, Shuen Iu Hung, Wen Hung Chung
• Other Authors: Xiamen Chang Gung Hospital
• Format: Article
• Published: 2020
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/60001
• Institution: Mahidol University

© 2020 American Academy of Allergy, Asthma & Immunology Background: Co-trimoxazole, a sulfonamide antibiotic, is used to treat a variety of infections worldwide, and it remains a common first-line medicine for prophylaxis against Pneumocystis jiroveci pneumonia. However, it can cause severe cu...