Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing.

Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing.

Whole genome sequencing (WGS) of Plasmodium vivax is problematic due to the reliance on clinical isolates which are generally low in parasitaemia and sample volume. Furthermore, clinical isolates contain a significant contaminating background of host DNA which confounds efforts to map short read se...

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Main Authors: Auburn, Sarah, Marfurt, Jutta, Maslen, Gareth, Campino, Susana, Rubio, Valentin Ruano, Manske, Magnus, MacHunter, Barbara, Kenangalem, Enny, Noviyanti, Rintis, Trianty, Leily, Sebayang, Boni, Wirjanata, Grennady, Kanlaya Sriprawat, Alcock ,Daniel, MacInnis, Bronwyn, Miotto, Olivo, Clark, Taane G., Russell, Bruce, Anstey, Nicholas M., Nosten, Franc¸ois, Kwiatkowski, Dominic P.
Format: Article
Language:English
Published: 2014
Subjects:
Genome, Protozoan
Humans
Malaria, Vivax
Open Access article
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/667
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Institution: Mahidol University
Language: English

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https://repository.li.mahidol.ac.th/handle/123456789/667

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