Protein-based signatures of functional evolution in Plasmodium falciparum

Protein-based signatures of functional evolution in Plasmodium falciparum

BACKGROUND: It has been known for over a decade that Plasmodium falciparum proteins are enriched in non-globular domains of unknown function. The potential for these regions of protein sequence to undergo high levels of genetic drift provides a fundamental challenge to attempts to identify the mole...

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Bibliographic Details
Main Authors: Gardner, Kate B., Sinha, Ipsita, Bustamante, Leyla Y., Day, Nicholas P.J., White, Nicholas J., Woodrow, Charles J.
Format: Article
Language:English
Published: 2013
Subjects:
Biological evolution
Cluster analysis
Computational biology
Genetic Drift
Hydrophobic and hydrophilic interactions
Mutation
Plasmodium falciparum
Open Access article
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/679
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Institution: Mahidol University
Language: English

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https://repository.li.mahidol.ac.th/handle/123456789/679

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