Differential Effects of a Novel Opioid Ligand UTA1003 on Antinociceptive Tolerance and Motor Behaviour
Analgesic tolerance is a major problem in the clinic for the maintenance of opioid-induced long-term pain relief. Opioids with mixed activity on multiple opioid receptors promise reduced antinociceptive tolerance in preclinical studies, but these compounds typically show poor bioavail-ability upon o...
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Main Authors: | Alok K. Paul, Krystel L. Woolley, Mohammed Rahmatullah, Polrat Wilairatana, Jason A. Smith, Nuri Gueven, Nikolas Dietis |
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Other Authors: | University of Cyprus Medical School |
Format: | Article |
Published: |
2022
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/73253 |
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Institution: | Mahidol University |
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