B1 repetitive sequence methylation enhances wound healing of second-degree burns in rats

• المؤلفون الرئيسيون: Jiraroch Meevassana, Panupong Nacharoenkul, Jade Wititsuwannakul, Nakarin Kitkumthorn, Kevin J. Hamill, Apichai Angspatt, Apiwat Mutirangura
• مؤلفون آخرون: Mahidol University, Faculty of Dentistry
• التنسيق: مقال
• منشور في: 2022
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Neuroscience; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/73407

The accumulation of DNA damage in burn wounds delays wound healing. DNA methylation by short interspersed nuclear element (SINE) small interfering (si) RNA prevents DNA damage and promotes cell proliferation. Therefore, SINE siRNA may be able to promote burn wound healing. Here, a SINE B1 siRNA was...