T cell mediated immunity against influenza H5N1 nucleoprotein, matrix and hemagglutinin derived epitopes in H5N1 survivors and non-H5N1 subjects

• Main Authors: Pirom Noisumdaeng, Thaneeya Roytrakul, Jarunee Prasertsopon, Phisanu Pooruk, Hatairat Lerdsamran, Susan Assanasen, Rungrueng Kitphati, Prasert Auewarakul, Pilaipan Puthavathana
• Other Authors: Siriraj Hospital
• Format: Article
• Published: 2022
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/75706
• Institution: Mahidol University

Background. Protection against the influenza virus by a specific antibody is relatively strain specific; meanwhile broader immunity may be conferred by cell-mediated immune response to the conserved epitopes across influenza virus subtypes. A universal broad-spectrum influenza vaccine which confront...