Pyruvate carboxylase supports basal ATP-linked respiration in human pluripotent stem cell-derived brown adipocytes

Brown adipocytes (BA) are a specialized fat cell which possesses a high capacity for fuel oxidation combined with heat production. The maintenance of high metabolic activity in BA requires elevated oxidation of fuel through the tricarboxylic acid cycle. Pyruvate carboxylase (PC) was previously propo...

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Bibliographic Details
Main Authors: Udom Lao-On, Timothy S. Cliff, Stephen Dalton, Sarawut Jitrapakdee
Other Authors: University of Georgia
Format: Article
Published: 2022
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76027
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Institution: Mahidol University