Structure, mechanism and regulation of pyruvate carboxylase
PC (pyruvate carboxylase) is a biotin-containing enzyme that catalyses the HCO3-- and MgATP-dependent carboxylation of pyruvate to form oxaloacetate. This is a very important anaplerotic reaction, replenishing oxaloacetate withdrawn from the tricarboxylic acid cycle for various pivotal biochemical p...
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Main Authors: | , , , , , |
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Other Authors: | |
Format: | Review |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/18883 |
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Institution: | Mahidol University |