Cyclooxygenase-2 inhibitory activity of chromone compounds by comparative molecular field analysis (Comfa)
Comparative molecular field analysis (CoMFA) study of chromone compounds as selective COX-2 inhibitor was aimed to derive the structural requirements for higher inhibitory activity. A data set of 36 compounds was divided into training set and test set by k-means clustering analysis based on the biol...
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Main Authors: | , |
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Format: | Article |
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2022
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/76110 |
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Institution: | Mahidol University |