Cyclooxygenase-2 inhibitory activity of chromone compounds by comparative molecular field analysis (Comfa)

Comparative molecular field analysis (CoMFA) study of chromone compounds as selective COX-2 inhibitor was aimed to derive the structural requirements for higher inhibitory activity. A data set of 36 compounds was divided into training set and test set by k-means clustering analysis based on the biol...

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Bibliographic Details
Main Authors: Wanlaya Laosumrit, Jiraporn Ungwitayatorn
Other Authors: Mahidol University
Format: Article
Published: 2022
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76110
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Institution: Mahidol University