BRET-based assay to specifically monitor β<inf>2</inf>AR/GRK2 interaction and β-arrestin2 conformational change upon βAR stimulation
The β-adrenergic receptors (βARs) are members of G protein-coupled receptor (GPCR) family and have been one of the most important GPCRs for studying receptor endocytosis and signaling pathway. Agonist binding of βARs leads to an activation of G proteins and their canonical effectors. In a parallel w...
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Main Authors: | , , , |
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Format: | Book Chapter |
Published: |
2022
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/76361 |
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Institution: | Mahidol University |