Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.

Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.

BACKGROUND: One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. METHODS: We p...

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Bibliographic Details
Main Authors: Zongo, Issaka, Some, Fabrice A., Somda, Serge A. M., Parikh, Sunil, Rouamba, Noel, Rosenthal, Philip J., Tarning, Joel, Lindegardh, Niklas, Nosten, Franc¸ois, Oue´draogo, Jean Bosco
Format: Article
Language:English
Published: 2015
Subjects:
African children
Concentrations
Dihydroartemisinin-Piperaquine
Malaria
Plasma
Open Access article
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/767
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Institution: Mahidol University
Language: English

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https://repository.li.mahidol.ac.th/handle/123456789/767

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