Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.
BACKGROUND: One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. METHODS: We p...
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Main Authors: | Zongo, Issaka, Some, Fabrice A., Somda, Serge A. M., Parikh, Sunil, Rouamba, Noel, Rosenthal, Philip J., Tarning, Joel, Lindegardh, Niklas, Nosten, Franc¸ois, Oue´draogo, Jean Bosco |
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Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/767 |
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Institution: | Mahidol University |
Language: | English |
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