Nanocapsules with excellent biocompatibility and stability in protein solutions

Nanocapsules with excellent biocompatibility and stability in protein solutions

Silica nanocapsules (SiO2NCs) are usually prepared with cationic surfactants that are not cytocompatible. Dialysis can be used to remove surfactants but leads to instability of the SiO2NCs when they are in the presence of proteins or biological media. Herein, SiO2NCs stabilized with a reactive surfa...

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Main Authors: Arjaree Jobdeedamrong, Man Theerasilp, Norased Nasongkla, Daniel Crespy
Other Authors: Vidyasirimedhi Institute of Science and Technology
Format: Article
Published: 2022
Subjects:
Engineering
Materials Science
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76932
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spelling th-mahidol.769322022-08-04T15:54:13Z Nanocapsules with excellent biocompatibility and stability in protein solutions Arjaree Jobdeedamrong Man Theerasilp Norased Nasongkla Daniel Crespy Vidyasirimedhi Institute of Science and Technology Mahidol University Engineering Materials Science Silica nanocapsules (SiO2NCs) are usually prepared with cationic surfactants that are not cytocompatible. Dialysis can be used to remove surfactants but leads to instability of the SiO2NCs when they are in the presence of proteins or biological media. Herein, SiO2NCs stabilized with a reactive surfactant are synthesized to prevent leaching upon dialysis. The SiO2NCs show superior stability and biocompatibility compared with SiO2NCs prepared with conventional surfactants. The SiO2NCs can be used in self-healing materials, smart agriculture and biomedical applications. 2022-08-04T08:34:55Z 2022-08-04T08:34:55Z 2021-09-07 Article Biomaterials Science. Vol.9, No.17 (2021), 5781-5784 10.1039/d1bm00510c 20474849 20474830 2-s2.0-85113739703 https://repository.li.mahidol.ac.th/handle/123456789/76932 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85113739703&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Engineering
Materials Science
spellingShingle Engineering
Materials Science
Arjaree Jobdeedamrong
Man Theerasilp
Norased Nasongkla
Daniel Crespy
Nanocapsules with excellent biocompatibility and stability in protein solutions
description Silica nanocapsules (SiO2NCs) are usually prepared with cationic surfactants that are not cytocompatible. Dialysis can be used to remove surfactants but leads to instability of the SiO2NCs when they are in the presence of proteins or biological media. Herein, SiO2NCs stabilized with a reactive surfactant are synthesized to prevent leaching upon dialysis. The SiO2NCs show superior stability and biocompatibility compared with SiO2NCs prepared with conventional surfactants. The SiO2NCs can be used in self-healing materials, smart agriculture and biomedical applications.
author2 Vidyasirimedhi Institute of Science and Technology
author_facet Vidyasirimedhi Institute of Science and Technology
Arjaree Jobdeedamrong
Man Theerasilp
Norased Nasongkla
Daniel Crespy
format Article
author Arjaree Jobdeedamrong
Man Theerasilp
Norased Nasongkla
Daniel Crespy
author_sort Arjaree Jobdeedamrong
title Nanocapsules with excellent biocompatibility and stability in protein solutions
title_short Nanocapsules with excellent biocompatibility and stability in protein solutions
title_full Nanocapsules with excellent biocompatibility and stability in protein solutions
title_fullStr Nanocapsules with excellent biocompatibility and stability in protein solutions
title_full_unstemmed Nanocapsules with excellent biocompatibility and stability in protein solutions
title_sort nanocapsules with excellent biocompatibility and stability in protein solutions
publishDate 2022
url https://repository.li.mahidol.ac.th/handle/123456789/76932
_version_ 1763495978709549056

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