Nanocapsules with excellent biocompatibility and stability in protein solutions

• Main Authors: Arjaree Jobdeedamrong, Man Theerasilp, Norased Nasongkla, Daniel Crespy
• Other Authors: Vidyasirimedhi Institute of Science and Technology
• Format: Article
• Published: 2022
• Subjects: Engineering; Materials Science
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76932
• Institution: Mahidol University

Silica nanocapsules (SiO2NCs) are usually prepared with cationic surfactants that are not cytocompatible. Dialysis can be used to remove surfactants but leads to instability of the SiO2NCs when they are in the presence of proteins or biological media. Herein, SiO2NCs stabilized with a reactive surfa...