Human transbodies to reverse transcriptase connection subdomain of hiv-1 gag-pol polyprotein reduce infectiousness of the virus progeny

Human transbodies to reverse transcriptase connection subdomain of hiv-1 gag-pol polyprotein reduce infectiousness of the virus progeny

HIV-1 progeny are released from infected cells as immature particles that are unable to infect new cells. Gag-Pol polyprotein dimerization via the reverse transcriptase connection domain (RTCDs) is pivotal for proper activation of the virus protease (PR protein) in an early event of the progeny viru...

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Bibliographic Details
Main Authors: Watee Seesuay, Siratcha Phanthong, Jaslan Densumite, Kodchakorn Mahasongkram, Nitat Sookrung, Wanpen Chaicumpa
Other Authors: Siriraj Hospital
Format: Article
Published: 2022
Subjects:
Immunology and Microbiology
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/77244
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/77244

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