Human transbodies to reverse transcriptase connection subdomain of hiv-1 gag-pol polyprotein reduce infectiousness of the virus progeny
HIV-1 progeny are released from infected cells as immature particles that are unable to infect new cells. Gag-Pol polyprotein dimerization via the reverse transcriptase connection domain (RTCDs) is pivotal for proper activation of the virus protease (PR protein) in an early event of the progeny viru...
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Main Authors: | Watee Seesuay, Siratcha Phanthong, Jaslan Densumite, Kodchakorn Mahasongkram, Nitat Sookrung, Wanpen Chaicumpa |
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Other Authors: | Siriraj Hospital |
Format: | Article |
Published: |
2022
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/77244 |
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Institution: | Mahidol University |
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