Plasma Ferritin as Marker of Macrophage Activation-Like Syndrome in Critically Ill Patients With Community-Acquired Pneumonia

• Main Authors: Xanthe Brands, Floris M.C. De Vries, Fabrice Uhel, Bastiaan W. Haak, Hessel Peters-Sengers, Alex R. Schuurman, Tjitske S.R. Van Engelen, René Lutter, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Brendon P. Scicluna, Tom Van Der Poll
• Other Authors: Amsterdam institute for Infection and Immunity
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/77708
• Institution: Mahidol University

OBJECTIVES: Plasma ferritin levels above 4,420 ng/mL have been proposed as a diagnostic marker for macrophage activation-like syndrome in sepsis and used for selection of sepsis patients for anti-inflammatory therapy. We here sought to determine the frequency, presentation, outcome, and host respons...