A mechanistic perspective on targeting bacterial drug resistance with nanoparticles

• Main Authors: Khatereh Khorsandi, Saeedeh Keyvani-Ghamsari, Fedora Khatibi Shahidi, Reza Hosseinzadeh, Simab Kanwal
• Other Authors: Islamic Azad University, Karaj Branch
• Format: Review
• Published: 2022
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/78984
• Institution: Mahidol University

Bacterial infections are an important cause of mortality worldwide owing to the prevalence of drug resistant bacteria. Bacteria develop resistance against antimicrobial drugs by several mechanisms such as enzyme inactivation, reduced cell permeability, modifying target site or enzyme, enhanced efflu...