Pharmacodynamics and Pharmacokinetics of Injectable Pimobendan and Its Metabolite, O-Desmethyl-Pimobendan, in Healthy Dogs

Objectives: This study was designed to thoroughly evaluate the effects of bolus pimobendan at a dose of 0.15 mg/kg on cardiac functions, hemodynamics, and electrocardiographic parameters together with the pharmacokinetic profile of pimobendan and its active metabolite, o-desmethyl-pimobendan (ODMP),...

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Bibliographic Details
Main Authors: Poonavit Pichayapaiboon, Lalida Tantisuwat, Pakit Boonpala, Nakkawee Saengklub, Tussapon Boonyarattanasoonthorn, Phisit Khemawoot, Anusak Kijtawornrat
Other Authors: Chulalongkorn University
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/79150
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Institution: Mahidol University