Pharmacodynamics and Pharmacokinetics of Injectable Pimobendan and Its Metabolite, O-Desmethyl-Pimobendan, in Healthy Dogs
Objectives: This study was designed to thoroughly evaluate the effects of bolus pimobendan at a dose of 0.15 mg/kg on cardiac functions, hemodynamics, and electrocardiographic parameters together with the pharmacokinetic profile of pimobendan and its active metabolite, o-desmethyl-pimobendan (ODMP),...
Saved in:
Main Authors: | Poonavit Pichayapaiboon, Lalida Tantisuwat, Pakit Boonpala, Nakkawee Saengklub, Tussapon Boonyarattanasoonthorn, Phisit Khemawoot, Anusak Kijtawornrat |
---|---|
Other Authors: | Chulalongkorn University |
Format: | Article |
Published: |
2022
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/79150 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
Similar Items
-
Preliminary Bioequivalence of an Oral Pimobendan Solution Formulation with Reference Solution Formulation in Beagle Dogs
by: Nakkawee Saengklub, et al.
Published: (2022) -
Preliminary Bioequivalence of an Oral Pimobendan Solution Formulation with Reference Solution Formulation in Beagle Dogs
by: Saengklub N.
Published: (2023) -
Pimobendan prevents cardiac dysfunction, mitigates cardiac mitochondrial dysfunction, and preserves myocyte ultrastructure in a rat model of mitral regurgitation
by: Boonpala P.
Published: (2023) -
Comparing potential drug–drug interactions in companion animal medications using two electronic databases
by: Tussapon Boonyarattanasoonthorn, et al.
Published: (2022) -
Long-term effect of sildenafil on echocardiographic parameters in dogs with asymptomatic myxomatous mitral valve degeneration
by: Anusak Kijtawornrat, et al.
Published: (2018)