Modified cycloartanes with improved inhibitory effect on SGLT-mediated glucose uptake in human renal proximal tubular cells
Sodium/glucose co-transporters (SGLTs) play an important role in renal glucose reabsorption. Inhibition of SGLT2 by derivatives of O-glucoside phlorizin dihydrochalcones has been approved for treatment of type 2 diabetes. The present study searches for the inhibitory effect of schisandronic acid (4)...
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Main Authors: | , , , , |
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Format: | Article |
Published: |
2022
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/79400 |
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Institution: | Mahidol University |