Modified cycloartanes with improved inhibitory effect on SGLT-mediated glucose uptake in human renal proximal tubular cells

Sodium/glucose co-transporters (SGLTs) play an important role in renal glucose reabsorption. Inhibition of SGLT2 by derivatives of O-glucoside phlorizin dihydrochalcones has been approved for treatment of type 2 diabetes. The present study searches for the inhibitory effect of schisandronic acid (4)...

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Bibliographic Details
Main Authors: Napason Chabang, Sirima Soodvilai, Bamroong Munyoo, Patoomratana Tuchinda, Sunhapas Soodvilai
Other Authors: Rangsit University
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/79400
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Institution: Mahidol University

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