Induction of fetal hemoglobin: Lentiviral shRNA knockdown of HBS1L in β<sup>0</sup>thalassemia/HbE erythroid cells
Imbalanced globin chain output contributes to thalassemia pathophysiology. Hence, induction of fetal hemoglobin in β-thalassemia and other β-hemoglobinopathies are of continuing interest for therapeutic approaches. Genome-wide association studies have identified three common genetic loci: namely β-g...
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Format: | Article |
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2023
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/82145 |
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Institution: | Mahidol University |