The roles of HMGB1-produced DNA gaps in DNA protection and aging biomarker reversal
The endogenous DNA damage triggering an aging progression in the elderly is prevented in the youth, probably by naturally occurring DNA gaps. Decreased DNA gaps are found during chronological aging in yeast. So we named the gaps “Youth-DNA-GAPs.” The gaps are hidden by histone deacetylation to preve...
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| Format: | Article |
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2023
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/83728 |
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| Institution: | Mahidol University |