Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders
Bioengineering of viral vectors for therapeutic gene delivery is a pivotal strategy to reduce doses, facilitate manufacturing, and improve efficacy and patient safety. Here, we engineered myotropic adeno-associated viral (AAV) vectors via a semirational, combinatorial approach that merges AAV capsid...
Saved in:
Main Author: | El Andari J. |
---|---|
Other Authors: | Mahidol University |
Format: | Article |
Published: |
2023
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/86470 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
Similar Items
-
A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors
by: Koollawat Chupradit, et al.
Published: (2022) -
A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors
by: Chupradit K.
Published: (2023) -
Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
by: Gan, Shu Uin, et al.
Published: (2021) -
Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice
by: Recino, Asha, et al.
Published: (2021) -
Extensions and decompositions of semirings
by: Pornchai Satravaha
Published: (2013)