Human monoclonal antibody fragments that neutralize bio-functions of surface exposed proteins of type a influenza viruses

• المؤلف الرئيسي: Tippawan Pissawong
• مؤلفون آخرون: Wanpen Chaicumpa
• اللغة: English
• منشور في: Mahidol University. Mahidol University Library and Knowledge Center 2023
• الموضوعات: Influenza A virus; Hemagglutinin; Neuraminidase; Cell Surface Display Techniques; Molecular Docking Simulation
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/89511

The surface proteins of the influenza A virus, namely hemagglutinin (HA), neuraminidase (NA), and matrix protein-2 (M2) are surface exposed and thus are vulnerable targets for neutralizing antibodies. HA is the most abundant protein on the viral surface and the virus uses this protein as a ligand fo...