Nanostring-based multigene assay to predict recurrence for gastric cancer patients after surgery

by Lee, J., Sohn, I., Do, I.-G., Kim, K.-M., Park, S.H., Park, J.O., Park, Y.S., Lim, H.Y., Sohn, T.S., Bae, J.M., Choi, M.G., Lim, D.H., Min, B.H., Lee, J.H., Rhee, P.L., Kim, J.J., Choi, D.I., Tan, I.B., Das, K., Tan, P., Jung, S.H., Kang, W.K., Kim, S.
Published 2014

Autophagy governs protumorigenic effects of mitotic slippage-induced senescence

by Jakhar, Rekha, Luijten, Monique N. H., Wong, Alex X. F., Cheng, Bing, Guo, Ke, Neo, Suat P., Au, Bijin, Kulkarni, Madhura, Lim, Kah J., Maimaiti, Jiamila, Chong, Han Chung, Lim, Elaine H., Tan, Tee B. K., Ong, Kong W., Sim, Yirong, Wong, Jill S. L., Khoo, James B. K., Ho, Juliana T. S., Chua, Boon T., Sinha, Indrajit, Wang, Xiaomeng, Connolly, John E., Gunaratne, Jayantha, Crasta, Karen Carmelina
Published 2020

Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis

by Zhang, W.C., Ng, S.-C., Yang, H., Rai, A., Umashankar, S., Ma, S., Soh, B.S., Sun, L.L., Tai, B.C., Nga, M.E., Bhakoo, K.K., Jayapal, S.R., Nichane, M., Yu, Q., Ahmed, D.A., Tan, C., Sing, W.P., Tam, J., Thirugananam, A., Noghabi, M.S., Pang, Y.H., Ang, H.S., Robson, P., Kaldis, P., Soo, R.A., Swarup, S., Lim, E.H., Lim, B.
Published 2014

High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer

by Tan I.B., Malik S., Ramnarayanan K., McPherson J.R., Ho D.L., Suzuki Y., Ng S.B., Yan S., Lim K.H., Koh D., Hoe C.M., Chan C.Y., Ten R., Goh B.K.P., Chung A.Y.F., Tan J., Chan C.X., Tay S.T., Alexander L., Nagarajan N., Hillmer A.M., Tang C.L., Chua C., Teh B.T., Rozen S., Tan P.
Published 2018

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets

by Deng, N., Goh, L.K., Wang, H., Das, K., Tao, J., Tan, I.B., Zhang, S., Lee, M., Wu, J., Lim, K.H., Lei, Z., Goh, G., Lim, Q.-Y., Tan, A.L.-K., Poh, D.Y.S., Riahi, S., Bell, S., Shi, M.M., Linnartz, R., Zhu, F., Yeoh, K.G., Toh, H.C., Yong, W.P., Cheong, H.C., Rha, S.Y., Boussioutas, A., Grabsch, H., Rozen, S., Tan, P.
Published 2014

Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy

by Tan, I.B., Ivanova, T., Lim, K.H., Ong, C.W., Deng, N., Lee, J., Tan, S.H., Wu, J., Lee, M.H., Ooi, C.H., Rha, S.Y., Wong, W.K., Boussioutas, A., Yeoh, K.G., So, J., Yong, W.P., Tsuburaya, A., Grabsch, H., Toh, H.C., Rozen, S., Cheong, J.H., Noh, S.H., Wan, W.K., Ajani, J.A., Lee, J., Tellez, M.S., Tan, P.
Published 2014

Autophagy governs protumorigenic effects of mitotic slippage-induced senescence

by Jakhar, R, Luijten, M.N.H, Wong, A.X.F, Cheng, B, Guo, K, Neo, S.P, Au, B, Kulkarni, M, Lim, K.J, Maimaiti, J, Chong, H.C, Lim, E.H, Tan, T.B.K, Ong, K.W, Sim, Y, Wong, J.S.L, Khoo, J.B.K, Ho, J.T.S, Chua, B.T, Sinha, I, Wang, X, Connolly, J.E, Gunaratne, J, Crasta, K.C
Published 2020

Platelet inhibition to target reperfusion injury trial: Rationale and study design

by Bulluck, Heerajnarain, Chan, Mervyn HH, Bryant, Jennifer A, Chai, Ping, Chawla, Ashish, Chua, Terrance S, Chung, Yiu-Cho, Fei, Gao, Ho, Hee H, Ho, Andrew FW, Hoe, Andrew J, Imran, Syed S, Lee, Chi-Hang, Lim, Swee H, Liew, Boon W, Yun, Patrick LZ, Hock, Marcus OE, Paradies, Valeria, Roe, Matthew T, Teo, Lynette, Wong, Aaron S, Wong, Evelyn, Wong, Philip E, Watson, Timothy, Chan, Mark Y, Tan, Jack W, Hausenloy, Derek J
Published 2021

Up to 206 Million People Reached and Over 5.4 Million Trained in Cardiopulmonary Resuscitation Worldwide: The 2019 International Liaison Committee on Resuscitation World Restart a...

by Böttiger, B.W., Lockey, A., Aickin, R., Carmona, M., Cassan, P., Castrén, M., Chakra Rao, S., De Caen, A., Escalante, R., Georgiou, M., Hoover, A., Kern, K.B., Khan, A.M.S., Levi, C., Lim, S.H., Nadkarni, V., Nakagawa, N.V., Nation, K., Neumar, R.W., Nolan, J.P., Mellin-Olsen, J., Pagani, J., Sales, M., Semeraro, F., Stanton, D., Toporas, C., van Grootven, H., Wang, T.-L., Wijesuriya, N., Wong, G., Perkins, G.D.
Published 2021

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

by Nahar, R, Zhai, W, Zhang, T, Takano, A, Khng, A.J, Lee, Y.Y, Liu, X, Lim, C.H, Koh, T.P.T, Aung, Z.W, Lim, T.K.H, Veeravalli, L, Yuan, J, Teo, A.S.M, Chan, C.X, Poh, H.M, Chua, I.M.L, Liew, A.A, Lau, D.P.X, Kwang, X.L, Toh, C.K, Lim, W.-T, Lim, B, Tam, W.L, Tan, E.-H, Hillmer, A.M, Tan, D.S.W
Published 2020

Exome sequencing of liver flukeg-associated cholangiocarcinoma

by Ong, C.K., Subimerb, C., Pairojkul, C., Wongkham, S., Cutcutache, I., Yu, W., McPherson, J.R., Allen, G.E., Ng, C.C.Y., Wong, B.H., Myint, S.S., Rajasegaran, V., Heng, H.L., Gan, A., Zang, Z.J., Wu, Y., Wu, J., Lee, M.H., Huang, D., Ong, P., Chan-On, W., Cao, Y., Qian, C.-N., Lim, K.H., Ooi, A., Dykema, K., Furge, K., Kukongviriyapan, V., Sripa, B., Wongkham, C., Yongvanit, P., Futreal, P.A., Bhudhisawasdi, V., Rozen, S., Tan, P., Teh, B.T.
Published 2013

Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis

by Rao, S.P.S., Lakshminarayana, S.B., Kondreddi, R.R., Herve, M., Camacho, L.R., Bifani, P., Kalapala, S.K., Jiricek, J., Ma, N.L., Tan, B.H., Ng, S.H., Nanjundappa, M., Ravindran, S., Seah, P.G., Thayalan, P., Lim, S.H., Lee, B.H., Goh, A., Barnes, W.S., Chen, Z., Gagaring, K., Chatterjee, A.K., Pethe, K., Kuhen, K., Walker, J., Feng, G., Babu, S., Zhang, L., Blasco, F., Beer, D., Weaver, M., Dartois, V., Glynne, R., Dick, T., Smith, P.W., Diagana, T.T., Manjunatha, U.H.
Published 2016

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

by Zang, Z.J., Cutcutache, I., Poon, S.L., Zhang, S.L., Mcpherson, J.R., Tao, J., Rajasegaran, V., Heng, H.L., Deng, N., Gan, A., Lim, K.H., Ong, C.K., Huang, D., Chin, S.Y., Tan, I.B., Ng, C.C.Y., Yu, W., Wu, Y., Lee, M., Wu, J., Poh, D., Wan, W.K., Rha, S.Y., So, J., Salto-Tellez, M., Yeoh, K.G., Wong, W.K., Zhu, Y.-J., Futreal, P.A., Pang, B., Ruan, Y., Hillmer, A.M., Bertrand, D., Nagarajan, N., Rozen, S., Teh, B.T., Tan, P.
Published 2013

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers

by Chan-On, W., Nairismägi, M.-L., Ong, C.K., Lim, W.K., Dima, S., Pairojkul, C., Lim, K.H., McPherson, J.R., Cutcutache, I., Heng, H.L., Ooi, L., Chung, A., Chow, P., Cheow, P.C., Lee, S.Y., Choo, S.P., Tan, I.B.H., Duda, D., Nastase, A., Myint, S.S., Wong, B.H., Gan, A., Rajasegaran, V., Ng, C.C.Y., Nagarajan, S., Jusakul, A., Zhang, S., Vohra, P., Yu, W., Huang, D., Sithithaworn, P., Yongvanit, P., Wongkham, S., Khuntikeo, N., Bhudhisawasdi, V., Popescu, I., Rozen, S.G., Tan, P., Teh, B.T.
Published 2014

Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing

by Ng, C.C.Y., Md Nasir, N.D., Loke, B.N., Tay, T.K.Y., Thike, A.A., Rajasegaran, V., Liu, W., Lee, J.Y., Guan, P., Lim, A.H., Chang, K.T.E., Gudi, M.A., Madhukumar, P., Tan, B.K.T., Tan, V.K.M., Wong, C.Y., Yong, W.S., Ho, G.H., Ong, K.W., Rahman, N.A., Begum, S.M.K.N., Cheah, Phaik Leng, Chen, C.J., Fuente, E.D., Han, A., Harada, O., Kanomata, N., Lee, C.S., Lee, J.Y.H., Kamal, M., Nishimura, R., Ohi, Y., Sawyer, E.J., Teoh, K.H., Tsang, A.K.H., Tsang, J.Y.-S., Tse, G.M.K., Yamaguchi, R., Yip, G.W.C., Bay, B.H., Tan, P., Teh, B.T., Tan, P.H., Consortium, International Fibroepithelial
Published 2021

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

by Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J.-F., Ahluwalia, T.V.S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T.O., Kleber, M.E., Crozier, S.R., Godfrey, K.M., Lemaitre, R., Felix, J.F., Shi, Y., Gupta, P., Khor, C.-C., Lehtimäki, T., Wang, C.A., Tiesler, C.M.T., Thiering, E., Standl, M., Rzehak, P., Marouli, E., He, M., Lecoeur, C., Corella, D., Lai, C.-Q., Moreno, L.A., Pitkänen, N., Boreham, C.A., Zhang, T., Saw, S.M., Ridker, P.M., Graff, M., van Rooij, F.J.A., Uitterlinden, A.G., Hofman, A., van Heemst, D., Rosendaal, F.R., de Mutsert, R., Burkhardt, R., Schulz, C.-A., Ericson, U., Kamatani, Y., Yuan, J.-M., Power, C., Hansen, T., Sørensen, T.I.A., Tjønneland, A., Overvad, K., Delgado, G., Cooper, C., Djousse, L., Rivadeneira, F., Jameson, K., Zhao, W., Liu, J., Lee, N.R., Raitakari, O., Kähönen, M., Viikari, J., Grote, V., Langhendries, J.-P., Koletzko, B., Escribano, J., Verduci, E., Dedoussis, G., Yu, C., Tham, Y.C., Lim, B., Lim, S.H., Froguel, P., Balkau, B., Fink, N.R., Vinding, R.K., Sevelsted, A., Bisgaard, H., Coltell, O., Dallongeville, J., Gottrand, F., Pahkala, K., Niinikoski, H., Hyppönen, E., Pedersen, O., März, W., Inskip, H., Jaddoe, V.W.V., Dennison, E., Wong, T.Y., Sabanayagam, C., Tai, E.-S., Mohlke, K.L., Mackey, D.A., Gruszfeld, D., Deloukas, P., Tucker, K.L., Fumeron, F., Bønnelykke, K., Rossing, P., Estruch, R., Ordovas, J.M., Arnett, D.K., Meirhaeghe, A., Amouyel, P., Cheng, C.-Y., Sim, X., Teo, Y.Y., van Dam, R.M., Koh, W.-P., Orho-Melander, M., Loeffler, M., Kubo, M., Thiery, J., Mook-Kanamori, D.O., Mozaffarian, D., Psaty, B.M., Franco, O.H., Wu, T., North, K.E., Davey Smith, G., Chavarro, J.E., Chasman, D.I., Qi, L., BIRTH-GENE (BIG) Study Working Group.
Published 2022

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

by Wheeler E., Leong A., Liu C.-T., Hivert M.-F., Strawbridge R.J., Podmore C., Li M., Yao J., Sim X., Hong J., Chu A.Y., Pereira M.A., Peters A., Ridker P.M., Sabanayagam C., Sale M., Saleheen D., Saltevo J., Schwarz P.E.H., Sheu W.H.H., Chang L.-C., Müller-Nurasyid M., Snieder H., Spector T.D., Tabara Y., Tuomilehto J., van Dam R.M., Wilson J.G., Wilson J.F., Wolffenbuttel B.H.R., Chen W.-M., Elks C.E., Nagaraja R., Evans D.S., Fan Q., Giulianini F., Go M.J., Hottenga J.-J., Hu Y., Jackson A.U., Kanoni S., Kim Y.J., Kleber M.E., Nauck M., Ladenvall C., Lecoeur C., Lim S.-H., Lu Y., Mahajan A., Marzi C., Nalls M.A., Navarro P., Nolte I.M., Rose L.M., Pankow J.S., Rybin D.V., Sanna S., Shi Y., Stram D.O., Takeuchi F., Tan S.P., van der Most P.J., Van Vliet-Ostaptchouk J.V., Wong A., Yengo L., Polasek O., Zhao W., Goel A., Martinez Larrad M.T., Radke D., Salo P., Tanaka T., van Iperen E.P.A., Abecasis G., Afaq S., Alizadeh B.Z., Prokopenko I., Bertoni A.G., Bonnefond A., Böttcher Y., Bottinger E.P., Campbell H., Carlson O.D., Chen C.-H., Cho Y.S., Garvey W.T., Gieger C., Ramos P.S., Goodarzi M.O., Grallert H., Hamsten A., Hartman C.A., Herder C., Hsiung C.A., Huang J., Igase M., Isono M., Katsuya T., Rasmussen-Torvik L., Khor C.-C., Kiess W., Kohara K., Kovacs P., Lee J., Lee W.-J., Lehne B., Li H., Liu J., Lobbens S., Rathmann W., Luan J., Lyssenko V., Meitinger T., Miki T., Miljkovic I., Moon S., Mulas A., Müller G., Rich S.S., Zhang W., Robertson N.R., Roden M., Roussel R., Rudan I., Scott R.A., Scott W.R., Sennblad B., Siscovick D.S., Strauch K., Sun L., Wang X., Swertz M., Tajuddin S.M., Taylor K.D., Teo Y.-Y., Tham Y.C., Tönjes A., Wareham N.J., Willemsen G., Wilsgaard T., Hingorani A.D., Chen P., Egan J., Ferrucci L., Hovingh G.K., Jula A., Kivimaki M., Kumari M., Njølstad I., Palmer C.N.A., Serrano Ríos M., Stumvoll M., Maruthur N.M., Watkins H., Aung T., Blüher M., Boehnke M., Boomsma D.I., Bornstein S.R., Chambers J.C., Chasman D.I., Chen Y.-D.I., Chen Y.-T., Porneala B.C., Cheng C.-Y., Cucca F., de Geus E.J.C., Deloukas P., Evans M.K., Fornage M., Friedlander Y., Froguel P., Groop L., Gross M.D., Sharp S.J., Harris T.B., Hayward C., Heng C.-K., Ingelsson E., Kato N., Kim B.-J., Koh W.-P., Kooner J.S., Körner A., Kuh D., Jia Y., Kuusisto J., Laakso M., Lin X., Liu Y., Loos R.J.F., Magnusson P.K.E., März W., McCarthy M.I., Oldehinkel A.J., Ong K.K., Kabagambe E.K., Pedersen N.L.
Published 2020