Biomimicking fiber platform with tunable stiffness to study mechanotransduction reveals stiffness enhances oligodendrocyte differentiation but impedes myelination through YAP-depen...

by Ong, William, Marinval, Nicolas, Lin, Junquan, Nai, Mui Hoon, Chong, Yee-Song, Pinese, Coline, Sajikumar, Sreedharan, Lim, Chwee Teck, Ffrench-Constant, Charles, Bechler, Marie E., Chew, Sing Yian
Published 2020

Loss of Caᵥ1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory

by Zhai, Jing, Navakkode, Sheeja, Yeow, Sean Qing Zhang, Krishna-K, Kumar, Liang, Mui Cheng, Koh, Joanne Huifen, Wong, Rui Xiong, Yu, Wei Ping, Sajikumar, Sreedharan, Huang, Hua, Soong, Tuck Wah
Published 2023

Hydroxychloroquine lowers Alzheimer's disease and related dementias risk and rescues molecular phenotypes related to Alzheimer's disease

by Varma, Vijay RR, Desai, Rishi JJ, Navakkode, Sheeja, Wong, Lik-Wei, Anerillas, Carlos, Loeffler, Tina, Schilcher, Irene, Mahesri, Mufaddal, Chin, Kristyn, Horton, Daniel BB, Kim, Seoyoung CC, Gerhard, Tobias, Segal, Jodi BB, Schneeweiss, Sebastian, Gorospe, Myriam, Sajikumar, Sreedharan, Thambisetty, Madhav
Published 2023

Glucose derived carbon nanosphere (CSP) conjugated TTK21, an activator of the histone acetyltransferases CBP/p300, ameliorates amyloid-beta 1-42 induced deficits in plasticity and...

by Singh, Akash K., Neo, Sin H., Liwang, Christine, Pang, Karen K. L., Leng, Jason C. K., Sinha, Sarmistha H., Shetty, Mahesh S., Vasudevan, Madavan, Rao, Vinay J., Joshi, Ila, Eswaramoorthy, Muthusamy, Pavon, Maria V., Sheila, Ang R., Navakkode, Sheeja, Kundu, Tapas K., Sajikumar, Sreedharan
Published 2023