Germline hemizygous deletion of CDKN2A-CDKN2B locus in a patient presenting with Li-Fraumeni syndrome

by Chan, S.H, Lim, W.K, Michalski, S.T, Lim, J.Q, Ishak, N.D.B, Met-Domestici, M, Young, C.N.C, Vikstrom, K, Esplin, E.D, Fulbright, J, Ang, M.K, Wee, J, Sittampalam, K, Farid, M, Lincoln, S.E, Itahana, K, Abdullah, S, Teh, B.T, Ngeow, J
Published 2020

Correction to: Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders (Genetics in Medicine, (2018), 10.1038/s41436-0...

by Bylstra Y., Kuan J.L., Lim W.K., Bhalshankar J.D., Teo J.X., Davila S., Teh B.T., Rozen S., Tan E.-C., Liew W.K.M., Yeo K.K., Tan P., Saw S.M., Cheng C.-Y., Cook S., Foo R., Jamuar S.S., The SinGapore Incidental Finding (SGIF) study group
Published 2019

Derivation and characterization of human fetal MSCs: An alternative cell source for large-scale production of cardioprotective microparticles

by Lai, R.C., Tan, S.S., Chen, T.S., Teh, B.J., Sidik, H., Lim, S.K., Arslan, F., Pasterkamp, G., de, Kleijn D.P.V., Tan, B., Tanavde, V., CHOO BOON HWA,ANDRE, Lee, M.M., Eng, J.K.L., Hwang, W.S., Lee, C.N., Oakley, R.M.E., Tan, K.H.
Published 2011

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

by Vettore A.L., Ramnarayanan K., Poore G., Lim K., Ong C.K., Huang K.K., Leong H.S., Chong F.T., Lim T.K.-H., Lim W.K., Cutcutache I., Mcpherson J.R., Suzuki Y., Zhang S., Skanthakumar T., Wang W., Tan D.S.W., Cho B.C., Teh B.T., Rozen S., Tan P., Iyer N.G.
Published 2018

Birt-Hogg-Dubé renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression

by Klomp J.A., Petillo D., Niemi N.M., Dykema K.J., Chen J., Yang X.J., Sääf A., Zickert P., Aly M., Bergerheim U., Nordenskjöld M., Gad S., Giraud S., Denoux Y., Yonneau L., Méjean A., Vasiliu V., Richard S., MacKeigan J.P., Teh B.T., Furge K.A.
Published 2018

Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated ELGN2-mediated oxygen-sensing response

by Koeman, J.M., Russell, R.C., Tan, M.-H., Petillo, D., Westphal, M., Koelzer, K., Metcalf, J.L., Zhang, Z., Matsuda, D., Dykema, K.J., Houseman, H.L., Kort, E.J., Furge, L.L., Kahnoski, R.J., Richard, S., Vieillefond, A., Swiatek, P.J., Teh, B.T., Ohh, M., Furge, K.A.
Published 2016

Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas

by Chan, S.H, Lim, W.K, Ishak, N.D.B, Li, S.-T, Goh, W.L, Tan, G.S, Lim, K.H, Teo, M, Young, C.N.C, Malik, S, Tan, M.H, Teh, J.Y.H, Chin, F.K.C, Kesavan, S, Selvarajan, S, Tan, P, Teh, B.T, Soo, K.C, Farid, M, Quek, R, Ngeow, J
Published 2020

Identification of molecular subtypes of gastric cancer with different responses to pi3-kinase inhibitors and 5-fluorouracil

by Lei, Z., Tan, I.B., Das, K., Deng, N., Zouridis, H., Pattison, S., Chua, C., Feng, Z., Guan, Y.K., Ooi, C.H., Ivanova, T., Zhang, S., Lee, M., Wu, J., Ngo, A., Manesh, S., Tan, E., Teh, B.T., So, J.B.Y., Goh, L.K., Boussioutas, A., Lim, T.K.H., Flotow, H., Tan, P., Rozen, S.G.
Published 2014

Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma

by Tan, M.-H., Wong, C.F., Tan, H.L., Yang, X.J., Ditlev, J., Matsuda, D., Khoo, S.K., Sugimura, J., Fujioka, T., Furge, K.A., Kort, E., Giraud, S., Ferlicot, S., Vielh, P., Amsellem-Ouazana, D., Debré, B., Flam, T., Thiounn, N., Zerbib, M., Benoît, G., Droupy, S., Molinié, V., Vieillefond, A., Tan, P.H., Richard, S., Teh, B.T.
Published 2016

VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail

by Evans, A.J, Russell, R.C, Roche, O, Burry, T.N, Fish, J.E, Chow, V.W.K, Kim, W.Y, Saravanan, A, Maynard, M.A, Gervais, M.L, Sufan, R.I, Roberts, A.M, Wilson, L.A, Betten, M, Vandewalle, C, Berx, G, Marsden, P.A, Irwin, M.S, Teh, B.T, Jewett, M.A.S, Ohh, M
Published 2020

High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer

by Tan I.B., Malik S., Ramnarayanan K., McPherson J.R., Ho D.L., Suzuki Y., Ng S.B., Yan S., Lim K.H., Koh D., Hoe C.M., Chan C.Y., Ten R., Goh B.K.P., Chung A.Y.F., Tan J., Chan C.X., Tay S.T., Alexander L., Nagarajan N., Hillmer A.M., Tang C.L., Chua C., Teh B.T., Rozen S., Tan P.
Published 2018

Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck

by Huang, K.K, Jang, K.W, Kim, S, Kim, H.S, Kim, S.-M, Kwon, H.J, Kim, H.R, Yun, H.J, Ahn, M.J, Park, K.U, Ramnarayanan, K, McPherson, J.R, Zhang, S, Rhee, J.-K, Vettore, A.L, Das, K, Ishimoto, T, Kim, J.H, Koh, Y.W, Kim, S.H, Choi, E.C, Teh, B.T, Rozen, S.G, Kim, T.-M, Tan, P, Cho, B.C
Published 2020

Janus kinase 3-activating mutations identifi ed in natural killer/T-cell lymphoma

by Koo, G.C., Tan, S.Y., Tang, T., Poon, S.L., Allen, G.E., Tan, L., Chong, S.C., Ong, W.S., Tay, K., Tao, M., Quek, R., Loong, S., Yeoh, K.-W., Yap, S.P., Lee, K.A., Lim, L.C., Tan, D., Goh, C., Cutcutache, I., Yu, W., Ng, C.C.Y., Rajasegaran, V., Heng, H.L., Gan, A., Ong, C.K., Rozen, S., Tan, P., Teh, B.T., Lim, S.T.
Published 2013

Genomic profiling reveals mutational landscape in parathyroid carcinomas

by Wang, C, Sun, J, Guillaume, B, Ge, T, Hibar, D.P, Greenwood, C.M.T, Qiu, A, The Alzheimer's Disease Neuroimaging Initiative, Pandya, C, Uzilov, A.V, Bellizzi, J, Lau, C.Y, Moe, A.S, Strahl, M, Hamou, W, Newman, L.C, Fink, M.Y, Antipin, Y, Yu, W, Stevenson, M, Cavaco, B.M, Teh, B.T, Thakker, R.V, Morreau, H, Schadt, E.E, Sebra, R, Li, S.D, Arnold, A, Chen, R
Published 2020

Exome sequencing of liver flukeg-associated cholangiocarcinoma

by Ong, C.K., Subimerb, C., Pairojkul, C., Wongkham, S., Cutcutache, I., Yu, W., McPherson, J.R., Allen, G.E., Ng, C.C.Y., Wong, B.H., Myint, S.S., Rajasegaran, V., Heng, H.L., Gan, A., Zang, Z.J., Wu, Y., Wu, J., Lee, M.H., Huang, D., Ong, P., Chan-On, W., Cao, Y., Qian, C.-N., Lim, K.H., Ooi, A., Dykema, K., Furge, K., Kukongviriyapan, V., Sripa, B., Wongkham, C., Yongvanit, P., Futreal, P.A., Bhudhisawasdi, V., Rozen, S., Tan, P., Teh, B.T.
Published 2013

Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer

by Huang K.K., Ramnarayanan K., Zhu F., Srivastava S., Xu C., Tan A.L.K., Lee M., Tay S., Das K., Xing M., Fatehullah A., Alkaff S.M.F., Lim T.K.H., Lee J., Ho K.Y., Rozen S.G., Teh B.T., Barker N., Chia C.K., Khor C., Ooi C.J., Fock K.M., So J., Lim W.C., Ling K.L., Ang T.L., Wong A., Rao J., Rajnakova A., Lim L.G., Yap W.M., Teh M., Yeoh K.G., Tan P.
Published 2018

Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity

by Ooi, W.F, Xing, M, Xu, C, Yao, X, Ramlee, M.K, Lim, M.C, Cao, F, Lim, K, Babu, D, Poon, L.-F, Lin Suling, J, Qamra, A, Irwanto, A, Qu Zhengzhong, J, Nandi, T, Lee-Lim, A.P, Chan, Y.S, Tay, S.T, Lee, M.H, Davies, J.O.J, Wong, W.K, Soo, K.C, Chan, W.H, Ong, H.S, Chow, P, Wong, C.Y, Rha, S.Y, Liu, J, Hillmer, A.M, Hughes, J.R, Rozen, S, Teh, B.T, Fullwood, M.J, Li, S, Tan, P
Published 2020

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

by Zang, Z.J., Cutcutache, I., Poon, S.L., Zhang, S.L., Mcpherson, J.R., Tao, J., Rajasegaran, V., Heng, H.L., Deng, N., Gan, A., Lim, K.H., Ong, C.K., Huang, D., Chin, S.Y., Tan, I.B., Ng, C.C.Y., Yu, W., Wu, Y., Lee, M., Wu, J., Poh, D., Wan, W.K., Rha, S.Y., So, J., Salto-Tellez, M., Yeoh, K.G., Wong, W.K., Zhu, Y.-J., Futreal, P.A., Pang, B., Ruan, Y., Hillmer, A.M., Bertrand, D., Nagarajan, N., Rozen, S., Teh, B.T., Tan, P.
Published 2013

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers

by Chan-On, W., Nairismägi, M.-L., Ong, C.K., Lim, W.K., Dima, S., Pairojkul, C., Lim, K.H., McPherson, J.R., Cutcutache, I., Heng, H.L., Ooi, L., Chung, A., Chow, P., Cheow, P.C., Lee, S.Y., Choo, S.P., Tan, I.B.H., Duda, D., Nastase, A., Myint, S.S., Wong, B.H., Gan, A., Rajasegaran, V., Ng, C.C.Y., Nagarajan, S., Jusakul, A., Zhang, S., Vohra, P., Yu, W., Huang, D., Sithithaworn, P., Yongvanit, P., Wongkham, S., Khuntikeo, N., Bhudhisawasdi, V., Popescu, I., Rozen, S.G., Tan, P., Teh, B.T.
Published 2014

Whole-genome reconstruction and mutational signatures in gastric cancer

by Nagarajan N., Bertrand D., Hillmer A.M., Zang Z.J., Yao F., Jacques P., Teo A.S., Cutcutache I., Zhang Z., Lee W.H., Sia Y.Y., Gao S., Ariyaratne P.N., Ho A., Woo X.Y., Veeravali L., Ong C.K., Deng N., Desai K.V., Khor C.C., Hibberd M.L., Shahab A., Rao J., Wu M., Teh M., Zhu F., Chin S.Y., Pang B., So J.B., Bourque G., Soong R., Sung W.-K., Tean Teh B., Rozen S., Ruan X., Yeoh K.G., Tan P.B., Ruan Y.
Published 2018