Repairing Mitochondrial Dysfunction in Disease

by Sorrentino, Vincenzo, Menzies, Keir J, Auwerx, Johan
Published 2024

Cytosolic Proteostasis Networks of the Nlitochondrial Stress Response

by D'Amico, Davide, Sorrentino, Vincenzo, Auwerx, Johan
Published 2024

Cross-species functional modules link proteostasis to human normal aging

by Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Kutalik, Zoltan, Auwerx, Johan, Robinson-Rechavi, Marc
Published 2024

Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models

by Cornaglia, Matteo, Krishnamani, Gopalan, Mouchiroud, Laurent, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin AM
Published 2024

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy

by Coquoz, Severine, Marchand, Paul J, Bouwens, Arno, Mouchiroud, Laurent, Sorrentino, Vincenzo, Szlag, Daniel, Auwerx, Johan, Lasser, Theo
Published 2024

NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

by Romani, Mario, Sorrentino, Vincenzo, Oh, Chang-Myung, Li, Hao, de Lima, Tanes Imamura, Zhang, Hongbo, Shong, Minho, Auwerx, Johan
Published 2024

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution

by Letizia, Maria Cristina, Cornaglia, Matteo, Trouillon, Raphael, Sorrentino, Vincenzo, Mouchiroud, Laurent, Sleiman, Maroun S Bou, Auwerx, Johan, Gijs, Martin AM
Published 2024

Track C. Biomedical Instrumentation & Micro and Nano Systems.

by Cornaglia, Matteo, Mouchiroud, Laurent, Krishnamani, Gopalan, Marette, Alexis, Narasimhan, Shreya, Jovaisaite, Virginija, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin AM
Published 2024

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

by D'Amico, Davide, Mottis, Adrienne, Potenza, Francesca, Sorrentino, Vincenzo, Li, Hao, Romani, Mario, Lemos, Vera, Schoonjans, Kristina, Zamboni, Nicola, Knott, Graham, Schneider, Bernard L, Auwerx, Johan
Published 2024

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

by Sorrentino, Vincenzo, Omani, Mario R, Ouchiroud, Laurent M, Beck, John S, Zhang, Hongbo, D'Amico, Davide, Moullan, Norman, Potenza, Francesca, Schmid, Adrien W, Rietsch, Solene, Counts, Scott E, Auwerx, Johan
Published 2024

PPARδ Promotes Running Endurance by Preserving Glucose

by Fan, Weiwei, Waizenegger, Wanda, Lin, Chun Shi, Sorrentino, Vincenzo, He, Ming-Xiao, Wall, Christopher E, Li, Hao, Liddle, Christopher, Yu, Ruth T, Atkins, Annette R, Auwerx, Johan, Downes, Michael, Evans, Ronald M
Published 2024

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

by McDaid, Aaron F, Joshi, Peter K, Porcu, Eleonora, Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Litovchenko, Maria, Bevers, Roel PJ, Rueger, Sina, Reymond, Alexandre, Bochud, Murielle, Deplancke, Bart, Williams, Robert W, Robinson-Rechavi, Marc, Paccaud, Fred, Rousson, Valentin, Auwerx, Johan, Wilson, James F, Kutalik, Zoltan
Published 2024

Bayesian Association Scan Reveals Novel Loci Associated with Human Lifespan and Pinpoints Causally Implicated Transcriptome Biomarkers

by McDaid, Aaron F, Joshi, Peter K, Porcu, Eleonora, Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Litovchenko, Maria, Bevers, Roel PJ, Rueger, Sina, Reymond, Alexandre, Bochud, Murielle, Deplancke, Bart, Williams, Robert W, Robinson-Rechavi, Marc, Paccaud, Fred, Rousson, Valentin, Auwerx, Johan, Wilson, James F, Kutalik, Zoltan
Published 2024

An Integrated Systems Genetics and Omics Toolkit to Probe Gene Function

by Li, Hao, Wang, Xu, Rukina, Daria, Huang, Qingyao, Lin, Tao, Sorrentino, Vincenzo, Zhang, Hongbo, Sleiman, Maroun Bou, Arends, Danny, McDaid, Aaron, Luan, Peiling, Ziari, Naveed, Velazquez-Villegas, Laura A, Gariani, Karim, Kutalik, Zoltan, Schoonjans, Kristina, Radcliffe, Richard A, Prins, Pjotr, Morgenthaler, Stephan, Williams, Robert W, Auwerx, Johan
Published 2024

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation

by Ryu, Dongryeol, Zhang, Hongbo, Ropelle, Eduardo R, Sorrentino, Vincenzo, Mazala, Davi AG, Mouchiroud, Laurent, Marshall, Philip L, Campbell, Matthew D, Ali, Amir Safi, Knowels, Gary M, Bellemin, Stephanie, Iyer, Shama R, Wang, Xu, Gariani, Karim, Sauve, Anthony A, Canto, Carles, Conley, Kevin E, Walter, Ludivine, Lovering, Richard M, Chin, Eva R, Jasmin, Bernard J, Marcinek, David J, Menzies, Keir J, Auwerx, Johan
Published 2024