Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor

by Sorrentino, Vincenzo, Zelcer, Noam
Published 2024

NAD(+) Metabolism and Interventions in Premature Renal Aging and Chronic Kidney Disease

by Chanvillard, Lucie, Tammaro, Alessandra, Sorrentino, Vincenzo
Published 2023

Repairing Mitochondrial Dysfunction in Disease

by Sorrentino, Vincenzo, Menzies, Keir J, Auwerx, Johan
Published 2024

Cytosolic Proteostasis Networks of the Nlitochondrial Stress Response

by D'Amico, Davide, Sorrentino, Vincenzo, Auwerx, Johan
Published 2024

Editorial: Mitochondria at the nexus of metabolism, aging, and disease

by Mallilankaraman, Karthik Babu, Kennedy, Brian K, Sorrentino, Vincenzo, Luciani, Alessandro
Published 2024

Distinct Functional Domains Contribute to Degradation of the Low Density Lipoprotein Receptor (LDLR) by the E3 Ubiquitin Ligase Inducible Degrader of the LDLR (IDOL)

by Sorrentino, Vincenzo, Scheer, Lilith, Santos, Ana, Reits, Eric, Bleijlevens, Boris, Zelcer, Noam
Published 2024

Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia

by Luciani, Alessandro, Denley, Matthew CS, Govers, Larissa P, Sorrentino, Vincenzo, Froese, D Sean
Published 2024

Cross-species functional modules link proteostasis to human normal aging

by Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Kutalik, Zoltan, Auwerx, Johan, Robinson-Rechavi, Marc
Published 2024

Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models

by Cornaglia, Matteo, Krishnamani, Gopalan, Mouchiroud, Laurent, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin AM
Published 2024

The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL

by Nelson, Jessica Kristine, Sorrentino, Vincenzo, Trezza, Rossella Avagliano, Heride, Claire, Urbe, Sylvie, Distel, Ben, Zelcer, Noam
Published 2024

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

by Sorrentino, Vincenzo, Nelson, Jessica K, Maspero, Elena, Marques, Andre RA, Scheer, Lilith, Polo, Simona, Zelcer, Noam
Published 2024

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy

by Coquoz, Severine, Marchand, Paul J, Bouwens, Arno, Mouchiroud, Laurent, Sorrentino, Vincenzo, Szlag, Daniel, Auwerx, Johan, Lasser, Theo
Published 2024

Boosting mitochondrial health to counteract neurodegeneration

by Burtscher, Johannes, Romani, Mario, Bernardo, Greta, Popa, Traian, Ziviani, Elena, Hummel, Friedhelm C, Sorrentino, Vincenzo, Millet, Gregoire P
Published 2024

NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

by Romani, Mario, Sorrentino, Vincenzo, Oh, Chang-Myung, Li, Hao, de Lima, Tanes Imamura, Zhang, Hongbo, Shong, Minho, Auwerx, Johan
Published 2024

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution

by Letizia, Maria Cristina, Cornaglia, Matteo, Trouillon, Raphael, Sorrentino, Vincenzo, Mouchiroud, Laurent, Sleiman, Maroun S Bou, Auwerx, Johan, Gijs, Martin AM
Published 2024

Track C. Biomedical Instrumentation & Micro and Nano Systems.

by Cornaglia, Matteo, Mouchiroud, Laurent, Krishnamani, Gopalan, Marette, Alexis, Narasimhan, Shreya, Jovaisaite, Virginija, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin AM
Published 2024

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

by Cook, Emma CL, Nelson, Jessica K, Sorrentino, Vincenzo, Koenis, Duco, Moeton, Martina, Scheij, Saskia, Ottenhoff, Roelof, Bleijlevens, Boris, Loregger, Anke, Zelcer, Noam
Published 2024

The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state

by Weiser, Anna, Hermant, Aurélie, Bermont, Flavien, Sizzano, Federico, Karaz, Sonia, Alvarez-Illera, Pilar, Santo-Domingo, Jaime, Sorrentino, Vincenzo, Feige, Jerome N, De Marchi, Umberto
Published 2023

Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein

by Sorrentino, Vincenzo, Fouchier, Sigrid W, Motazacker, Mohammad M, Nelson, Jessica K, Defesche, Joep C, Dallinga-Thie, Geesje M, Kastelein, John JP, Hovingh, G Kees, Zelcer, Noam
Published 2024

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

by D'Amico, Davide, Mottis, Adrienne, Potenza, Francesca, Sorrentino, Vincenzo, Li, Hao, Romani, Mario, Lemos, Vera, Schoonjans, Kristina, Zamboni, Nicola, Knott, Graham, Schneider, Bernard L, Auwerx, Johan
Published 2024