The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

10.1194/jlr.M037713

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Bibliographic Details
Main Authors: Sorrentino, Vincenzo, Nelson, Jessica K, Maspero, Elena, Marques, Andre RA, Scheer, Lilith, Polo, Simona, Zelcer, Noam
Other Authors: BIOCHEMISTRY
Format: Article
Language:English
Published: ELSEVIER 2024
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
liver X receptor
low density lipoprotein receptor
inducible degrader of low density lipoprotein receptor
E3-ubiquitin ligase
endocytosis
lipoprotein receptors
epsins
DENSITY-LIPOPROTEIN RECEPTOR
AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA
LIGASE INDUCIBLE DEGRADER
ADAPTER PROTEIN
COATED PITS
MEDIATED ENDOCYTOSIS
MEMBRANE-PROTEIN
FAMILIAL HYPERCHOLESTEROLEMIA
EPSIN 1
UBIQUITIN
Online Access:https://scholarbank.nus.edu.sg/handle/10635/247843
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Institution: National University of Singapore
Language: English

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https://scholarbank.nus.edu.sg/handle/10635/247843

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