The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

10.1194/jlr.M037713

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Main Authors: Sorrentino, Vincenzo, Nelson, Jessica K, Maspero, Elena, Marques, Andre RA, Scheer, Lilith, Polo, Simona, Zelcer, Noam
Other Authors: BIOCHEMISTRY
Format: Article
Language:English
Published: ELSEVIER 2024
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/247843
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-2478432024-11-08T19:55:31Z The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation Sorrentino, Vincenzo Nelson, Jessica K Maspero, Elena Marques, Andre RA Scheer, Lilith Polo, Simona Zelcer, Noam BIOCHEMISTRY Dr Vincenzo Sorrentino Science & Technology Life Sciences & Biomedicine Biochemistry & Molecular Biology liver X receptor low density lipoprotein receptor inducible degrader of low density lipoprotein receptor E3-ubiquitin ligase endocytosis lipoprotein receptors epsins DENSITY-LIPOPROTEIN RECEPTOR AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA LIGASE INDUCIBLE DEGRADER ADAPTER PROTEIN COATED PITS MEDIATED ENDOCYTOSIS MEMBRANE-PROTEIN FAMILIAL HYPERCHOLESTEROLEMIA EPSIN 1 UBIQUITIN 10.1194/jlr.M037713 JOURNAL OF LIPID RESEARCH 54 8 2174-2184 2024-04-11T08:49:28Z 2024-04-11T08:49:28Z 2013-08 2024-04-08T10:49:26Z Article Sorrentino, Vincenzo, Nelson, Jessica K, Maspero, Elena, Marques, Andre RA, Scheer, Lilith, Polo, Simona, Zelcer, Noam (2013-08). The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation. JOURNAL OF LIPID RESEARCH 54 (8) : 2174-2184. ScholarBank@NUS Repository. https://doi.org/10.1194/jlr.M037713 0022-2275 1539-7262 https://scholarbank.nus.edu.sg/handle/10635/247843 en ELSEVIER Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
liver X receptor
low density lipoprotein receptor
inducible degrader of low density lipoprotein receptor
E3-ubiquitin ligase
endocytosis
lipoprotein receptors
epsins
DENSITY-LIPOPROTEIN RECEPTOR
AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA
LIGASE INDUCIBLE DEGRADER
ADAPTER PROTEIN
COATED PITS
MEDIATED ENDOCYTOSIS
MEMBRANE-PROTEIN
FAMILIAL HYPERCHOLESTEROLEMIA
EPSIN 1
UBIQUITIN
spellingShingle Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
liver X receptor
low density lipoprotein receptor
inducible degrader of low density lipoprotein receptor
E3-ubiquitin ligase
endocytosis
lipoprotein receptors
epsins
DENSITY-LIPOPROTEIN RECEPTOR
AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA
LIGASE INDUCIBLE DEGRADER
ADAPTER PROTEIN
COATED PITS
MEDIATED ENDOCYTOSIS
MEMBRANE-PROTEIN
FAMILIAL HYPERCHOLESTEROLEMIA
EPSIN 1
UBIQUITIN
Sorrentino, Vincenzo
Nelson, Jessica K
Maspero, Elena
Marques, Andre RA
Scheer, Lilith
Polo, Simona
Zelcer, Noam
The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
description 10.1194/jlr.M037713
author2 BIOCHEMISTRY
author_facet BIOCHEMISTRY
Sorrentino, Vincenzo
Nelson, Jessica K
Maspero, Elena
Marques, Andre RA
Scheer, Lilith
Polo, Simona
Zelcer, Noam
format Article
author Sorrentino, Vincenzo
Nelson, Jessica K
Maspero, Elena
Marques, Andre RA
Scheer, Lilith
Polo, Simona
Zelcer, Noam
author_sort Sorrentino, Vincenzo
title The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
title_short The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
title_full The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
title_fullStr The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
title_full_unstemmed The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
title_sort lxr-idol axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for ldlr internalization and lysosomal degradation
publisher ELSEVIER
publishDate 2024
url https://scholarbank.nus.edu.sg/handle/10635/247843
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