Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration

by Sonntag, Tanja, Ancel, Sara, Karaz, Sonia, Cichosz, Paulina, Jacot, Guillaume, Giner, Maria Pilar, Sanchez-Garcia, Jose Luis, Pannerec, Alice, Moco, Sofia, Sorrentino, Vincenzo, Canto, Carles, Feige, Jerome N
Published 2024

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation

by Ryu, Dongryeol, Zhang, Hongbo, Ropelle, Eduardo R, Sorrentino, Vincenzo, Mazala, Davi AG, Mouchiroud, Laurent, Marshall, Philip L, Campbell, Matthew D, Ali, Amir Safi, Knowels, Gary M, Bellemin, Stephanie, Iyer, Shama R, Wang, Xu, Gariani, Karim, Sauve, Anthony A, Canto, Carles, Conley, Kevin E, Walter, Ludivine, Lovering, Richard M, Chin, Eva R, Jasmin, Bernard J, Marcinek, David J, Menzies, Keir J, Auwerx, Johan
Published 2024

Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

by Membrez, Mathieu, Migliavacca, Eugenia, Christen, Stefan, Yaku, Keisuke, Trieu, Jennifer, Lee, Alaina K, Morandini, Francesco, Giner, Maria Pilar, Stiner, Jade, Makarov, Mikhail V, Garratt, Emma S, Vasiloglou, Maria F, Chanvillard, Lucie, Dalbram, Emilie, Ehrlich, Amy M, Sanchez-Garcia, José Luis, Canto, Carles, Karagounis, Leonidas G, Treebak, Jonas T, Migaud, Marie E, Heshmat, Ramin, Razi, Farideh, Karnani, Neerja, Ostovar, Afshin, Farzadfar, Farshad, Tay, Stacey KH, Sanders, Matthew J, Lillycrop, Karen A, Godfrey, Keith M, Nakagawa, Takashi, Moco, Sofia, Koopman, René, Lynch, Gordon S, Sorrentino, Vincenzo, Feige, Jerome N
Published 2024