Identification of MET genomic amplification, protein expression and alternative splice isoforms in neuroblastomas

by Yan, B., Lim, M., Zhou, L., Kuick, C.H., Leong, M.Y., Yong, K.J., Aung, L., Salto-Tellez, M., Chang, K.T.E.
Published 2014

Intra-operative cerebrospinal fluid sampling versus post-operative lumbar puncture for detection of leptomeningeal disease in malignant paediatric brain tumours

by Low S.Y.Y., Wei C.M., Chang K.T.E., Huak C.Y., Ping N.L., Tew S.W., Low D.C.Y.
Published 2020

Enterovirus a71 infection activates human immune responses and induces pathological changes in humanized mice

by Ke, Y, Liu, WN, Her, Z, Liu, M, Tan, SY, Tan, YW, Chan, XY, Fan, Y, Huang, EK, Chen, H, Chang, KTE, Chan, JKY, Chu, JJH, Chen, Q
Published 2020

Platform comparison for evaluation of ALK protein immunohistochemical expression, genomic copy number and hotspot mutation status in neuroblastomas

by Yan B., Kuick C.H., Lim M., Venkataraman K., Tennakoon C., Loh E., Lian D., Leong M.Y., Lakshmanan M., Tergaonkar V., Sung W.-K., Soh S.Y., Chang K.T.E.
Published 2018

XAF1 promotes neuroblastoma tumor suppression and is required for KIF1B?-mediated apoptosis

by Choo, Z, Koh, R.Y.L, Wallis, K, Koh, T.J.W, Kuick, C.H, Sobrado, V, Kenchappa, R.S, Loh, A.H.P, Soh, S.Y, Schlisio, S, Chang, K.T.E, Chen, Z.X
Published 2020

Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics

by Yong, K.S.M., Her, Z., Tan, S.Y., Tan, W.W.S., Liu, M., Lai, F., Heng, S.M., Fan, Y., Chang, K.T.E., Wang, C.-I., Chan, J.K.Y., Chen, J., Chen, Q.
Published 2021

A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice /631/250/38 /631/250/256/2515 /13/21 article

by Gunawan, M, Her, Z, Liu, M, Tan, S.Y, Chan, X.Y, Tan, W.W.S, Dharmaraaja, S, Fan, Y, Ong, C.B, Loh, E, Chang, K.T.E, Tan, T.C, Chan, J.K.Y, Chen, Q
Published 2020

Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells

by Chen, Q., Amaladoss, A., Ye, W., Liu, M., Dummler, S., Kong, F., Wong, L.H., Loo, H.L., Loh, E., Tan, S.Q., Tan, T.C., Chang, K.T.E., Dao, M., Suresh, S., Preiser, P.R., Chen, J.
Published 2016

Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model

by Zheng Z., Sze C.W., Keng C.T., Al-Haddawi M., Liu M., Tan S.Y., Kwek H.L., Her Z., Chan X.Y., Barnwal B., Loh E., Chang K.T.E., Tan T.C., Tan Y.-J., Chen Q.
Published 2020

CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice

by Her, Z., Tan, J.H.L., Lim, Y.-S., Tan, S.Y., Chan, X.Y., Tan, W.W.S., Liu, M., Yong, K.S.M., Lai, F., Ceccarello, E., Zheng, Z., Fan, Y., Chang, K.T.E., Sun, L., Chang, S.C., Chin, C.-L., Lee, G.H., Dan, Y.Y., Chan, Y.-S., Lim, S.G., Chan, J.K.Y., Chandy, K.G., Chen, Q.
Published 2021

Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy

by Zhao Y., Shuen T.W.H., Toh T.B., Chan X.Y., Liu M., Tan S.Y., Fan Y., Yang H., Lyer S.G., Bonney G.K., Loh E., Chang K.T.E., Tan T.C., Zhai W., Chan J.K.Y., Chow E.K.-H., Chee C.E., Lee G.H., Dan Y.Y., Chow P.K.-H., Toh H.C., Lim S.G., Chen Q.
Published 2019

Neuroblastoma patient-derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response

by Hee, E., Wong, M.K., Tan, S.H., Choo, Z., Kuick, C.H., Ling, S., Yong, M.H., Jain, S., Lian, D.W.Q., Ng, E.H.Q., Yong, Y.F.L., Ren, M.H., Syed Sulaiman, N., Low, S.Y.Y., Chua, Y.W., Syed, M.F., Lim, T.K.H., Soh, S.Y., Iyer, P., Seng, M.S.F., Lam, J.C.M., Tan, E.E.K., Chan, M.Y., Tan, A.M., Chen, Y., Chen, Z., Chang, K.T.E., Loh, A.H.P.
Published 2021

VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma

by Yao, X, Tan, J, Lim, K.J, Koh, J, Ooi, W.F, Li, Z, Huang, D, Xing, M, Chan, Y.S, Qu, J.Z, Tay, S.T, Wijaya, G, Lam, Y.N, Hong, J.H, Lee-Lim, A.P, Guan, P, Ng, M.S.W, He, C.Z, Lin, J.S, Nandi, T, Qamra, A, Xu, C, Myint, S.S, Davies, J.O.J, Goh, J.Y, Loh, G, Tan, B.C, Rozen, S.G, Yu, Q, Tan, I.B.H, Cheng, C.W.S, Li, S, Chang, K.T.E, Tan, P.H, Silver, D.L, Lezhava, A, Steger, G, Hughes, J.R, Teh, B.T, Tan, P
Published 2020

Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing

by Ng, C.C.Y., Md Nasir, N.D., Loke, B.N., Tay, T.K.Y., Thike, A.A., Rajasegaran, V., Liu, W., Lee, J.Y., Guan, P., Lim, A.H., Chang, K.T.E., Gudi, M.A., Madhukumar, P., Tan, B.K.T., Tan, V.K.M., Wong, C.Y., Yong, W.S., Ho, G.H., Ong, K.W., Rahman, N.A., Begum, S.M.K.N., Cheah, Phaik Leng, Chen, C.J., Fuente, E.D., Han, A., Harada, O., Kanomata, N., Lee, C.S., Lee, J.Y.H., Kamal, M., Nishimura, R., Ohi, Y., Sawyer, E.J., Teoh, K.H., Tsang, A.K.H., Tsang, J.Y.-S., Tse, G.M.K., Yamaguchi, R., Yip, G.W.C., Bay, B.H., Tan, P., Teh, B.T., Tan, P.H., Consortium, International Fibroepithelial
Published 2021