NOVEL MOLECULAR MECHANISMS CONTROLLING MITOPHAGY

by CHO YIK LAM
Published 2023

A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery

by Tan, Hayden Weng Siong, Lu, Guang, Dong, Han, Cho, Yik-Lam, Natalia, Auginia, Wang, Liming, Chan, Charlene, Kappei, Dennis, Taneja, Reshma, Ling, Shuo-Chien, Shao, Huilin, Tsai, Shih-Yin, Ding, Wen-Xing, Shen, Han-Ming
Published 2023

FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons

by Ho, Wan Yun, Chak, Li-Ling, Hor, Jin-Hui, Liu, Fujia, Diaz-Garcia, Sandra, Chang, Jer-Cherng, Sanford, Emma, Rodriguez, Maria J., Alagappan, Durgadevi, Lim, Su Min, Cho, Yik-Lam, Shimizu, Yuji, Sun, Alfred Xuyang, Tyan, Sheue-Houy, Koo, Edward, Kim, Seung Hyun, Ravits, John, Ng, Shi-Yan, Okamura, Katsutomo, Ling, Shuo-Chien
Published 2024

DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death

by Low, Heng Boon, Wong, Zhen Lim, Wu, Bangyuan, Kong, Li Ren, Png, Chin Wen, Cho, Yik-Lam, Li, Chun-Wei, Xiao, Fengchun, Xin, Xuan, Yang, Henry, Loo, Jia Min, Lee, Fiona Yi Xin, Tan, Iain Bee Huat, DasGupta, Ramanuj, Shen, Han-Ming, Schwarz, Herbert, Gascoigne, Nicholas RJ, Goh, Boon Cher, Xu, Xiaohong, Zhang, Yongliang
Published 2021

PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy

by Wang, Liming, Cho, Yik-Lam, Tang, Yancheng, Wang, Jigang, Park, Jung-Eun, Wu, Yajun, Wang, Chunxin, Tong, Yan, Chawla, Ritu, Zhang, Jianbin, Shi, Yin, Deng, Shuo, Lu, Guang, Wu, Yihua, Tan, Hayden Weng-Siong, Pawijit, Pornteera, Lim, Grace Gui-Yin, Chan, Hui-Ying, Zhang, Jingzi, Fang, Lei, Yu, Hanry, Liou, Yih-Cherng, Karthik, Mallilankaraman, Bay, Boon-Huat, Lim, Kah-Leong, Sze, Siu-Kwan, Yap, Celestial T., Shen, Han-Ming
Published 2020