MiR-582-5p is a tumor suppressor microRNA targeting the Hippo-YAP/TAZ signaling pathway in non-small cell lung cancer

by Zhu, Bowen, Mitheera, V, Finch-Edmondson, Megan, Lee, Yaelim, Wan, Yue, Sudol, Marius, DasGupta, Ramanuj
Published 2022

Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures

by Suphavilai, Chayaporn, Chia, Shumei, Sharma, Ankur, Tu, Lorna, Da Silva, Rafael Peres, Mongia, Aanchal, DasGupta, Ramanuj, Nagarajan, Niranjan
Published 2022

Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction

by Low, Joo-Leng, Du, Weina, Gocha, Tenzin, Oguz, Gokce, Zhang, Xiaoqian, Chen, Ming Wei, Masirevic, Srdan, Yim, Daniel Guo Rong, Tan, Iain Bee Huat, Ramasamy, Adaikalavan, Fan, Hao, DasGupta, Ramanuj
Published 2022

Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2+ Liver Progenitor Cells: Implications in Coronavirus Disease 201...

by Seow, Justine Jia Wen, Pai, Rhea, Mishra, Archita, Shepherdson, Edwin, Lim, Tony Kiat Hon, Goh, Brian K. P., Chan, Jerry K. Y., Chow, Pierce K. H., Ginhoux, Florent, DasGupta, Ramanuj, Sharma, Ankur
Published 2022

The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

by Ahmed, Syed Moiz, Ramani, Priya Dharshana, Wong, Stephen Qi Rong, Zhao, Xiaodan, Ivanyi-Nagy, Roland, Leong, Tang Choong, Chua, Clarinda, Li, Zhizhong, Hentze, Hannes, Tan, Iain BeeHuat, Yan, Jie, DasGupta, Ramanuj, Dröge, Peter
Published 2019

Identification of mechanism of cancer-cell-specific reactivation of hTERT offers therapeutic opportunities for blocking telomerase specifically in human colorectal cancer

by Akıncılar, Semih Can, Chua, Joelle Yi Heng, Ng, Qin Feng, Chan, Claire Hian Tzer, Eslami-S, Zahra, Chen, Kaijing, Low, Joo-Leng, Arumugam, Surendar, Aswad, Luay, Chua, Clarinda, Tan, Iain Beehuat, DasGupta, Ramanuj, Fullwood, Melissa Jane, Tergaonkar, Vinay
Published 2023

Dynamic expression of tRNA-derived small RNAs define cellular states.

by Krishna, Srikar, Yim, Daniel Gr, Lakshmanan, Vairavan, Tirumalai, Varsha, Koh, Judice Ly, Park, Jung Eun, Cheong, Jit Kong, Low, Joo Leng, Lim, Michelle Js, Sze, Siu Kwan, Shivaprasad, Padubidri, Gulyani, Akash, Raghavan, Srikala, Palakodeti, Dasaradhi, DasGupta, Ramanuj
Published 2022

Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

by Ravasio, Andrea, Myaing, Myint Z, Chia, Shumei, Arora, Aditya, Sathe, Aneesh, Cao, Elaine Yiqun, Bertocchi, Cristina, Sharma, Ankur, Arasi, Bakya, Chung, Vin Yee, Greene, Adrienne C, Tan, Tuan Zea, Chen, Zhongwen, Ong, Hui Ting, Iyer, N Gopalakrishna, Huang, Ruby YunJu, DasGupta, Ramanuj, Groves, Jay T, Viasnoff, Virgile
Published 2021

Author Correction: Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

by Ravasio, Andrea, Myaing, Myint Z, Chia, Shumei, Arora, Aditya, Sathe, Aneesh, Cao, Elaine Yiqun, Bertocchi, Cristina, Sharma, Ankur, Arasi, Bakya, Chung, Vin Yee, Greene, Adrienne C, Tan, Tuan Zea, Chen, Zhongwen, Ong, Hui Ting, Iyer, N Gopalakrishna, Huang, Ruby YunJu, DasGupta, Ramanuj, Groves, Jay T, Viasnoff, Virgile
Published 2021

DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death

by Low, Heng Boon, Wong, Zhen Lim, Wu, Bangyuan, Kong, Li Ren, Png, Chin Wen, Cho, Yik-Lam, Li, Chun-Wei, Xiao, Fengchun, Xin, Xuan, Yang, Henry, Loo, Jia Min, Lee, Fiona Yi Xin, Tan, Iain Bee Huat, DasGupta, Ramanuj, Shen, Han-Ming, Schwarz, Herbert, Gascoigne, Nicholas RJ, Goh, Boon Cher, Xu, Xiaohong, Zhang, Yongliang
Published 2021

Rising global burden of cancer attributable to high BMI from 2010 to 2019

by Tan, Darren Jun Hao, Ng, Cheng Han, Muthiah, Mark, Yong, Jie Ning, Chee, Douglas, Teng, Margaret, Wong, Zhen Yu, Zeng, Rebecca Wenling, Chin, Yip Han, Wang, Jiong-Wei, Danpanichkul, Pojsakorn, Rajaram, Ruveena Bhavani, DasGupta, Ramanuj, Suzuki, Hiroyuki, Takahashi, Hirokazu, Tamaki, Nobuharu, Dan, Yock Young, Lui, Rashid, Duseja, Ajay, Siddiqui, Mohammad Shadab, Yeoh, Khay Guan, Sanyal, Arun, Wijarnpreecha, Karn, Loomba, Rohit, Mantzoros, Christos Socrates, Huang, Daniel Q.
Published 2024

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

by Sharma, Ankur, Seow, Justine Jia Wen, Dutertre, Charles-Antoine, Pai, Rhea, Bleriot, Camille, Mishra, Archita, Wong, Regina Men Men, Singh, Gurmit Singh Naranjan, Sudhagar, Samydurai, Khalilnezhad, Shabnam, Erdal, Sergio, Teo, Hui Min, Khalilnezhad, Ahad, Chakarov, Svetoslav, Lim, Tony Kiat Hon, Fui, Alexander Chung Yaw, Chieh, Alfred Kow Wei, Chung, Cheow Peng, Bonney, Glenn Kunnath, Goh, Brian Kim-Poh, Chan, Jerry KY, Chow, Pierce KH, Ginhoux, Florent, DasGupta, Ramanuj
Published 2021

Trajectory of immune evasion and cancer progression in hepatocellular carcinoma

by Nguyen, Phuong H. D., Wasser, Martin, Tan, Chong Teik, Lim, Chun Jye, Lai, Hannah L. H., Seow, Justine Jia Wen, DasGupta, Ramanuj, Phua, Cheryl Z. J., Ma, Siming, Yang, Jicheng, Sheena D/O Suthen, Tam, Wai Leong, Lim, Tony K. H., Yeong, Joe, Leow, Wei Qiang, Pang, Yin Huei, Soon, Gwyneth, Loh, Tracy Jiezhen, Wan, Wei Keat, Chan, Chung Yip, Cheow, Peng Chung, Toh, Han Chong, Kow, Alfred, Dan, Yock Young, Kam, Juinn Huar, Iyer, Shridhar, Madhavan, Krishnakumar, Chung, Alexander, Bonney, Glenn K., Goh, Brian K. P., Fu, Naiyang, Yu, Victor C., Zhai, Weiwei, Albani, Salvatore, Chow, Pierce K. H., Chew, Valerie
Published 2023