Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer

by Fang, Yiwen, Fullwood, Melissa Jane
Published 2016

MYC overexpression leads to increased chromatin interactions at superenhancers and MYC binding sites

by See, Yi Xiang, Chen, Kaijing, Fullwood, Melissa Jane
Published 2022

Chromatin interactions and regulatory elements in cancer : from bench to bedside

by See, Yi Xiang, Wang, Benny Zhengjie, Fullwood, Melissa Jane
Published 2020

Long-distance repression by human silencers: chromatin interactions and phase separation in silencers

by Zhang, Ying, See, Yi Xiang, Tergaonkar, Vinay, Fullwood, Melissa Jane
Published 2022

Accurate identification of DNA replication origin by fusing epigenomics and chromatin interaction information

by Dao, Fu-Ying, Lv, Hao, Fullwood, Melissa Jane, Lin, Hao
Published 2023

Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains

by Yeo, Samuel Jianjie, Ying, Chen, Fullwood, Melissa Jane, Tergaonkar, Vinay
Published 2023

Super-enhancers, phase-separated condensates, and 3D genome organization in cancer

by Tang, Seng Chuan, Vijayakumar, Udhaya, Zhang, Ying, Fullwood, Melissa Jane
Published 2023

A resource of ribosomal RNA-depleted RNA-Seq data from different normal adult and fetal human tissues

by Choy, Jocelyn Y. H., Boon, Priscilla L. S., Bertin, Nicolas, Fullwood, Melissa Jane
Published 2018

Chromatin loop anchors can predict transcript and exon usage

by Zhang, Yu, Cai, Yichao, Francesc Xavier, Roca Castella, Chee, Keong Kwoh, Fullwood, Melissa Jane
Published 2023

MCI-frcnn: a deep learning method for topological micro-domain boundary detection

by Tian, Simon Zhongyuan, Yin, Pengfei, Jing, Kai, Yang, Yang, Xu, Yewen, Huang, Guangyu, Ning, Duo, Fullwood, Melissa Jane, Zheng, Meizhen
Published 2023

Exploring the roles for repressive and quiescent chromatin regions in 3D organization of the human genome

by Cai, Yichao, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Babu, Deepak, An, Omer, Yang, Henry, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published 2019

NanoVar : accurate characterization of patients' genomic structural variants using low-depth nanopore sequencing

by Tham, Cheng Yong, Tirado-Magallanes, Roberto, Goh, Yufen, Fullwood, Melissa Jane, Koh, Bryan T. H., Wang, Wilson, Ng, Chin Hin, Chng, Wee Joo, Thiery, Alexandre, Tenen, Daniel G., Benoukraf, Touati
Published 2021

Chromatin interaction neural network (ChINN) : a machine learning-based method for predicting chromatin interactions from DNA sequences

by Cao, Fan, Zhang, Yu, Cai, Yichao, Animesh, Sambhavi, Zhang, Ying, Akincilar, Semih Can, Loh, Yan Ping, Li, Xinya, Chng, Wee Joo, Tergaonkar, Vinay, Kwoh, Chee Keong, Fullwood, Melissa Jane
Published 2021

Defining essential enhancers for pluripotent stem cells using a features-oriented CRISPR-Cas9 screen

by Wang, Hao Fei, Warrier, Tushar, Farran, Chadi A., Zheng, Zi Hao, Xing, Qiao Rui, Fullwood, Melissa Jane, Zhang, Li-Feng, Li, Hu, Xu, Jian, Lim, Tit-Meng, Loh, Yuin-Han
Published 2021

MCIBox: a toolkit for single-molecule multi-way chromatin interaction visualization and micro-domains identification

by Tian, Simon Zhongyuan, Li, Guoliang, Ning, Duo, Jing, Kai, Xu, Yewen, Yang, Yang, Fullwood, Melissa Jane, Yin, Pengfei, Huang, Guangyu, Plewczynski, Dariusz, Zhai, Jixian, Dai, Ziwei, Chen, Wei, Zheng, Meizhen
Published 2023

H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions

by Cai, Yichao, Zhang, Ying, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Cao, Zhendong, Raju, Anandhkumar, Lieberman Aiden, Erez, Li, Shang, Manikandan, Lakshmanan, Tergaonkar, Vinay, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published 2021

Profiling of 3D genome organization in nasopharyngeal cancer needle biopsy patient samples by a modified Hi-C approach

by Animesh, Sambhavi, Choudhary, Ruchi, Wong, Bertrand Jern Han, Koh, Charlotte Tze Jia, Ng, Xin Yi, Tay, Joshua Kai Xun, Chong, Wan-Qin, Jian, Han, Chen, Leilei, Goh, Boon Cher, Fullwood, Melissa Jane
Published 2022

H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions

by Cai, Yichao, Zhang, Ying, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Cao, Zhendong, Raju, Anandhkumar, Lieberman Aiden, Erez, Li, Shang, Manikandan, Lakshmanan, Tergaonkar, Vinay, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published 2022

Profiling of 3D Genome Organization in Nasopharyngeal Cancer Needle Biopsy Patient Samples by a Modified Hi-C Approach

by Animesh, Sambhavi, Choudhary, Ruchi, Wong, Bertrand Jern Han, Koh, Charlotte Tze Jia, Ng, Xin Yi, Tay, Joshua Kai Xun, Chong, Wan-Qin, Jian, Han, Chen, Leilei, Goh, Boon Cher, Fullwood, Melissa Jane
Published 2022

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

by Tan, Shi Hao, Leong, Wei Zhong, Ngoc, Phuong Cao Thi, Tan, Tze King, Bertulfo, Fatima Carla, Lim, Mei Chee, An, Omer, Li, Zhenhua, Yeoh, Allen Eng Juh, Tenen, Daniel G., Sanda, Takaomi, Fullwood, Melissa Jane
Published 2019