Long-distance repression by human silencers: chromatin interactions and phase separation in silencers

Three-dimensional genome organization represents an additional layer in the epigenetic regulation of gene expression. Active transcription controlled by enhancers or super-enhancers has been extensively studied. Enhancers or super-enhancers can recruit activators or co-activators to activate target...

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Bibliographic Details
Main Authors: Zhang, Ying, See, Yi Xiang, Tergaonkar, Vinay, Fullwood, Melissa Jane
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/160607
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Institution: Nanyang Technological University
Language: English